RABBIT ANTI PLECTIN
Rabbit anti Human plectin antibody recognizes plectin, also known as hemidesmosomal protein 1, plectin 1, PCN and intermediate filament binding protein 500 kDa.
Plectin is a prominent member of an important family of structurally termed plakins or cytolinkers that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. Expression of specific plectin isoforms were found to be dependent on cell type and stage of development. A number of groups reported that patients suffering from epidermolysis bullosa simplex with muscular dystrophy (EBS-MD) lacked plectin expression in skin and muscle tissues due to defects in the plectin gene . Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna (provided by RefSeq, Aug 2011).
Rabbit anti Human plectin antibody detect bands of 300-500 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Disponibilidad | Bajo pedido |
---|---|
Marca | BIO-RAD |
Recomendaciones
-
RPMI 1640 Medium, GlutaMAX™ Supplement33,76 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Polypropylene cryobox without compartment height 52 mm Blue5,30 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Frasco de cultivo de 75 cm² con superficie TC, cuello inclinado con forma de U y tapón ventilado, 100 Uds.322,76 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
MICROPLACAS 96 POCILLOS F-BOTTOM WITH LID STERILE281,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
DIAMOND TIPS, D1000, EASYPACK, BAG 100031,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Matriz extracelular de colágeno, tipo I de cola de rata, 1 vial 100 mg299,88 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Frasco de cultivo de 25 cm², cuello inclinado, rectangular con tapón ventilado, 200 Uds.333,86 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
-
Placa de cultivo de 100 mm superficie tratada para TC, 500 Uds.469,41 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Finnpipette Labtip Blue, 1000 ul, 1000/bag31,30 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
-
CARROUSEL PIPETTE HOLDER FOR 7 PIPETTES122,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
NuPAGE™ 10 %, Bis-Tris, 1,0–1,5 mm, geles de proteínas Mini214,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Brilliant Violet 421™ anti-mouse CD117 (c-kit),CLON ACK2, 500 μL503,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
-
PE anti-mouse CD16,CLON S17014E, 25 μg111,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
TotalSeq™-C0089 anti-human TIGIT (VSTM3),CLON A15153G, 10 μg444,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
ELISA MAX™ Deluxe Set Mouse IFN-γ, 10 Plates657,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Recombinant Mouse IL-25 (IL-17E) (insect expressed, CF), 10 μg258,00 € sin ivaPara ver tus precios y comprar Iniciar sesión
-
Laboratory balance 110-220 g_ 0,01-0,1m9.180,00 € sin ivaPara ver tus precios y comprar Iniciar sesión