RABBIT ANTI eEF1A1

Rabbit anti Human eEF1A1 antibody recognizes the elongation factor 1-alpha 1, also known as CTCL tumor antigen, EF1a-like protein, cervical cancer suppressor 3, elongation factor Tu, eukaryotic elongation factor 1 A-1, eukaryotic translation elongation factor 1 alpha 1-like 14, glucocorticoid receptor AF-1 specific elongation factor, leukocyte receptor cluster (LRC) member 7 or prostate tumor-inducing protein 1.

The EEF1A1 gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome (Ditzel et al.et al. 2000). EEF1A1 has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes (provided by RefSeq, Jul 2008).

Rabbit anti Human eEF1A1 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.