RABBIT ANTI 14-3-3 GAMMA

Rabbit anti Human 14-3-3 gamma antibody recognizes 14-3-3 protein gamma, also known as protein kinase C inhibitor protein 1, "protein phosphatase 1, regulatory subunit 170" or tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide.

The YWHAG gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways (provided by RefSeq, Jul 2008).

Rabbit anti Human 14-3-3 gamma antibody detects a band of 27 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.