Edit-R Mouse CRISPRa synthetic crRNA

The CRISPR activation (CRISPRa) system is a unique adaptation of the classical CRISPR-Cas9 gene editing system which utilizes a catalytically deactivated or dead S. pyogenes Cas9 (dCas9) that is fused to one or more transcriptional activators. When paired with a well-designed guide RNA that targets a gene near a promoter region, or trancriptional start site (TSS), it promotes transcriptional activation.